‍22. Mining coral-derived terpene synthases and mechanistic studies of the coral biflorane synthase‍ ‍   ‍ ‍

Bao Chen^#, Jingjing Mao^#, Kangwei Xu^#, Lijun Liu, Wei Lin, Yue-Wei Guo*, Ruibo Wu*, Chengyuan Wang*, Baofu Xu*

Sci. Adv., 2025, 11, eadv0805.

‍20.‍ Discovery of a terpene synthase synthesizing a nearly non-flexible eunicellane reveals the basis of flexibility‍‍‍‍

Jinfeng Li^#,Bao Chen^#,Zunyun Fu^#,Jingjing Mao^#,Lijun Liu,Xiaochen Chen,Mingyue Zheng,Chang-Yun Wang*,Chengyuan Wang*,Yue-Wei Guo*,Baofu Xu*

Nat. Commun., 2024, 15, 5940.

19.Chemical and Biosynthetic Potential of Penicillium shentong XL-F41

Ran Zou, Xin Li, Xiaochen Chen, Yue-Wei Guo, Baofu Xu*

Beilstein J. Org. Chem., 2024, 20, 597–606.

‍15.First trans-eunicellane terpene synthase in bacteria

Zining Li, Baofu Xu, Volga Kojasoy, Teresa Ortega, Donovon A. Adpressa, Wenbo Ning, Xiuting Wei, Jamin Liu, Dean J. Tantillo, Sandra Loesgen, Jeffrey D.Rudolf*

Chem, 2023, 9(3), 698–708

14.Recent advances of activation techniques-based discovery of new compounds from marine fungi

Ran Zou, Bao Chen, Jie Sun, Yue-Wei Guo, Baofu Xu*

Fitoterapia, 2023, 167, 105503.

13.Unusual Secondary Metabolites from the Mangrove Ecosystems: Structures, Bioactivities,Chemical, and Bio-Syntheses

Meng-Jun Wu, Baofu Xu*, Yue-Wei Guo

Mar. Drugs, 2022, 20, 535.

12.Bioactive Cembranoids from the Coral Sarcophyton trocheliophorum of Ximao Island

Zi-Rong Zeng, Jing Chen, Hong Wang, Hai-Yan Zhang, Jia Li, Baofu Xu*, Yue-Wei Guo*

ACS Omega, 2022, 7, 41678−41686.

11.Cytotoxicand and Antibacterial Isomalabaricane Terpenoids from the Sponge Rhabdastrella globostellata

BaoChen#, Pei Ju Qiu#, Baofu Xu#, Qingmin Zhao, Yu-Cheng Gu, Lei Fu, ShiJie Bi, Lefu Lan*, Chang-Yun Wang*, Yue-Wei Guo*

J. Nat. Prod., 2022, 85, 1799–1807.

10.‍‍‍Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability‍

Baofu Xu,Wenbo Ning, Xiuting Wei, Jeffrey D. Rudolf*

Org. Biomol. Chem., 2022, 20(45), 8833–8837.

9.Bacterial terpenome

Jeffrey D. Rudolf*, Tyler A. Alsup, Baofu Xu, Zining Li

Nat. Prod. Rep., 2021, 38, 905.

‍8.Mechanistic Insights into the Formation of the 6,10-Bicyclic Eunicellane Skeleton by the Bacterial Diterpene Synthase Bnd4

Baofu Xu, Dean J. Tantillo, Jeffrey D. Rudolf*

Angew. Chem. Int. Ed., 2021, 60, 23159–23163.

7.Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid

Chenxi Zhu^#, Baofu Xu^#, Donovon A. Adpressa^#, Jeffrey D. Rudolf*, Sandra Loesgen*

Angew. Chem. Int. Ed., 2021, 60, 14163–14170.

6.Bacterial diterpene synthases prenylate small molecules‍

Baofu Xu, Zining Li,Tyler A. Alsup, Michelle A. Ehrenberger,   Jeffrey D. Rudolf*

ACS Catal., 2021, 11(10), 5906–5915.

5.Building Microbial Hosts for Heterologous Production of N-Methylpyrrolinium

Yu Ping, Xiaodong Li, Baofu Xu, Wei Wei, Wenping Wei, Guoyin Kai, Zhihua Zhou*, Youli Xiao*

ACS Syn. Biol., 2019, 8, 257−263.

4.Insights into pipecolic acid biosynthesis in Huperzia serrata

Baofu Xu, Zhen Fan, Yongxing Lei, Yu Ping, Amit Jaisi, Youli Xiao*

Org. Lett., 2018, 20, 8, 2195–2198.

2.Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzymeand a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics

Nisha He, Pan Wu, Yongxing Lei, Baofu Xu, Xiaochen Zhu, Gudan Xu, Yaojie Gao,Jianzhao Qi, Zixin Deng, Gongli Tang, Wenqing Chen*, Youli Xiao*

Chem.Sci., 2017, 8, 444−451.

1.Identification and characterization of L-lysine decarboxylase from Huperzia serrata and its role in the metabolic pathway of lycopodium alkaloid‍

Baofu Xu, Lei Lei, Xiaocen Zhu, Yiqing Zhou, Youli Xiao*

Phytochemistry, 2017, 136: 23–30.