Publications

20.Discovery of a novel eunicellane synthase unveils the relationship between stereochemistry and flexibility among eunicellanes‍

Jinfeng Li ,Bao Chen ,Zunyun Fu ,Jingjing Mao ,Lijun Liu ,Xiaochen Chen ,Mingyue Zheng ,Chang-Yun Wang*,Chengyuan Wang*,Yue-Wei Guo*,Baofu Xu*

ChemRxiv. 2023; doi:10.26434/chemrxiv-2023-jzr1p-v2   This content is a preprint and has not been peer-reviewed.

19.Chemical and Biosynthetic Potential of Penicillium shentong XL-F41

Ran Zou, Xin Li, Xiaochen Chen, Yuewei Guo and Baofu Xu*

Beilstein J. Org. Chem. 2024, 20, 597–606.https://doi.org/10.3762/bjoc.20.52

18.Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells

Jia-Ling Lin, Longxian Chen, Wen-Kai Wu, Xiao-Xiang Guo, ChenHui Yu, Min Xu, Gui-Bin Nie, Jun-ling Dun, Yan Li, Baofu Xu, Ling-Jian Wang, Xiao-Ya Chen, Wei Gao*, Jin-Quan Huang*

Mol Plant. 2023;16(12):1990-2003. doi:10.1016/j.molp.2023.10.008

17.Cryptic isomerization in diterpene biosynthesis and the restoration of an evolutionarily defunct P450

Zining Li, Baofu Xu, Tyler Alsup, Xiuting Wei, Wenbo Ning, Daniel Icenhour, Michelle Ehrenberger, Ion Ghiviriga, Bao-Doan Giang, Jeffrey Rudolf*

J. Am. Chem. Soc. 2023, 145, 41, 22361–22365

16.Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds

Jia-Ling Lin, Xin Fang, Jian-Xu Li, Zhi-Wen Chen, Wen-Kai Wu, Xiao-Xiang Guo, Ning-Jing Liu, Jia-Fa Huang, Fang-Yan Chen, Ling-Jian Wang, Baofu Xu, Cathie Martin, Xiao-Ya Chen* & Jin-Quan Huang*

Nat.Plants, 2023;9(4):605-615

15.First trans-eunicellane terpene synthase in bacteria

Zining Li, Baofu Xu, Volga Kojasoy, Teresa Ortega, Donovon A. Adpressa, Wenbo Ning, Xiuting Wei, Jamin Liu, Dean J. Tantillo, Sandra Loesgen, and Jeffrey D.Rudolf*

Chem, 2023,9(3), 698-708

14.Recent advances of activation techniques-based discovery of new compounds from marine fungi

Ran Zou, Bao Chen, Jie Sun, Yue-Wei Guo , Baofu Xu*

Fitoterapia. 2023;167:105503

12.Bioactive Cembranoids from the Coral Sarcophyton trocheliophorum of Ximao Island

Zi-Rong Zeng, Jing Chen, Hong Wang, Hai-Yan Zhang, Jia Li, Baofu Xu*, Yue-Wei Guo*

ACS Omega, 2022, 7, 41678−41686

11.Cytotoxicand and Antibacterial Isomalabaricane Terpenoids from the Sponge Rhabdastrella globostellata

BaoChen#, Pei Ju Qiu#, Baofu Xu#, Qingmin Zhao, Yu-Cheng Gu, Lei Fu, ShiJie Bi, Lefu Lan*, Chang-Yun Wang*, Yue-Wei Guo*

J.Nat. Prod., 2022, 85, 1799–1807

10.‍‍‍Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability‍

Baofu Xu,Wenbo Ning, Xiuting Wei, and Jeffrey D. Rudolf*

Org.Biomol. Chem., 2022, 20, 45, 8833-8837

9.Bacterial terpenome

Jeffrey D. Rudolf*, Tyler A. Alsup, Baofu Xu, Zining Li

Nat.Prod. Rep., 2021, 38, 905

8.Mechanistic Insights into the Formation of the 6,10-Bicyclic Eunicellane Skeleton by the Bacterial Diterpene Synthase Bnd4

Baofu Xu, Prof. Dean J. Tantillo, Dr. Jeffrey D. Rudolf*

Angew. Chem. Int. Ed., 2021, 60, 23159–23163.

7.Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid

Chenxi Zhu#, Baofu Xu#, Donovon A. Adpressa#, Jeffrey D. Rudolf*, and Sandra Loesgen*

Angew. Chem. Int. Ed., 2021, 60, 14163–14170

6.Bacterial diterpene synthases prenylate small molecules‍

Baofu Xu,Zining Li,Tyler A. Alsup,Michelle A. Ehrenberger, and Jeffrey D. Rudolf*

ACS Catal. 2021, 11, 10, 5906–5915

5.Building Microbial Hosts for Heterologous Production of N-Methylpyrrolinium

Yu Ping, Xiaodong Li, Baofu Xu, Wei Wei, Wenping Wei, Guoyin Kai, Zhihua Zhou*, Youli Xiao*

ACS Syn. Biol., 2019, 8, 257−263

4.Insights into pipecolic acid biosynthesis in Huperzia serrata

Baofu Xu,Zhen Fan, Yongxing Lei, Yu Ping, Amit Jaisi, and Youli Xiao*

Org.Lett., 2018, 20, 8, 2195-2198

3.Global transcriptome analysis of Huperzia serrata and identification of critical genes involved in the biosynthesis of huperzine A

Mengquan Yang, Wenjing You, Shiwen Wu, Zhen Fan, Baofu Xu, Mulan Zhu, Xuan Li,Youli Xiao*

BMC Genomics, 2017, 18, 245

2.Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzymeand a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics

Nisha He, Pan Wu, Yongxing Lei, Baofu Xu, Xiaochen Zhu, Gudan Xu, Yaojie Gao,Jianzhao Qi, Zixin Deng, Gongli Tang, Wenqing Chen*, Youli Xiao*

Chem.Sci., 2017, 8, 444−451